Description

3-Chloro-n-Cyclopropyl-5-(Trifluoromethyl)Pyridin-2-Amine CAS NO 1031619-96-1 is a high-value, multi-functional pyridine derivative characterized by its unique trifluoromethyl and cyclopropyl substituents. This compound serves as a critical advanced intermediate in modern organic synthesis, enabling the development of novel molecules with enhanced biological activity and physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances lipophilicity and metabolic stability.
• Material Science Research: Acts as a precursor for specialized ligands and functional monomers in the development of advanced polymers and metal-organic frameworks (MOFs).
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client-specific projects.

Basic Information

Product Name	3-Chloro-n-Cyclopropyl-5-(Trifluoromethyl)Pyridin-2-Amine
CAS No.	1031619-96-1
Molecular Formula	C9H8ClF3N2
Molecular Weight	236.62 g/mol
Synonyms	3-Chloro-N-cyclopropyl-5-(trifluoromethyl)pyridin-2-amine; 2-Pyridinamine, 3-chloro-N-cyclopropyl-5-(trifluoromethyl)-; 3-Chloro-N-cyclopropyl-5-(trifluoromethyl)-2-pyridinamine; 1031619-96-1; 3-Chloro-N-cyclopropyl-5-trifluoromethylpyridin-2-amine; 3-Chloro-N-cyclopropyl-5-(trifluoromethyl)-2-aminopyridine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this advanced intermediate. Production follows current Good Manufacturing Practices (cGMP) where applicable, and every batch is analyzed using validated methods including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and residual solvents is provided with each shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.