Description

1-(6-Chloro-3-Nitro-2-Pyridinyl)-4-Hydroxy-2-Pyrrolidinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyridine-pyrrolidine hybrid structure. This compound is of significant commercial value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic and crop protection agents. Our supply is backed by stringent quality control to ensure batch-to-batch consistency for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Serves as a key synthon for developing new-generation pesticides and herbicides with specific mode-of-action targets.
• Chemical Biology & Proteomics: Used in the design and synthesis of molecular probes and enzyme inhibitors for biochemical pathway studies.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects requiring high-purity, complex heterocyclic compounds.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.
• Material Science Precursor: Investigated for the development of specialty chemicals and functional materials with specific electronic properties.

Basic Information

Product Name	1-(6-Chloro-3-Nitro-2-Pyridinyl)-4-Hydroxy-2-Pyrrolidinecarboxylic Acid
CAS No.	1031244-78-6
Molecular Formula	C10H10ClN3O5
Molecular Weight	287.66 g/mol
Synonyms	4-Hydroxy-1-(6-chloro-3-nitro-2-pyridinyl)-2-pyrrolidinecarboxylic acid; 2-Pyrrolidinecarboxylic acid, 1-(6-chloro-3-nitro-2-pyridinyl)-4-hydroxy-; 1-(6-Chloro-3-nitro-2-pyridyl)-4-hydroxy-pyrrolidine-2-carboxylic acid; (2S,4R)-1-(6-Chloro-3-nitro-2-pyridinyl)-4-hydroxy-2-pyrrolidinecarboxylic acid (for stereoisomer); 1031244-78-6; 6-Chloro-3-nitro-2-pyridine substituted pyrrolidinecarboxylic acid derivative
EINECS	Contact for details

Quality Control

Every batch of 1-(6-Chloro-3-Nitro-2-Pyridinyl)-4-Hydroxy-2-Pyrrolidinecarboxylic Acid is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and conformity to client specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. Our quality protocols are designed to meet the rigorous standards required for pharmaceutical R&D and GMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.