Description

5-(3-Aminothieno[2,3-B]Pyridin-2-Yl)-4-(2-Furylmethyl)-4H-1,2,4-Triazole-3-Thiol is a sophisticated heterocyclic organic compound featuring a fused thienopyridine core linked to a triazole-thiol moiety, representing a high-value building block for advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to create new entities with targeted biological or functional properties.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Employed in the research and synthesis of novel active ingredients for crop protection products.
• Material Science Precursor: Acts as a building block for creating specialized organic materials, such as ligands for metal-organic frameworks (MOFs) or functional polymers.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects requiring complex heterocycles.

Basic Information

Item	Detail
Product Name	5-(3-Aminothieno[2,3-B]Pyridin-2-Yl)-4-(2-Furylmethyl)-4H-1,2,4-Triazole-3-Thiol
CAS No.	1030433-39-6
Molecular Formula	C14H11N5OS2
Molecular Weight	329.40 g/mol
Synonyms	5-(3-Aminothieno[2,3-b]pyridin-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazole-3-thiol; 4-(2-Furanylmethyl)-5-(3-amino[1]benzothieno[2,3-b]pyridin-2-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione; 1030433-39-6; AKOS025147064; CS-0336226; FT-0773296; NS00093827; 4-(furan-2-ylmethyl)-5-(3-aminothieno[2,3-b]pyridin-2-yl)-4H-1,2,4-triazole-3-thiol
EINECS	Contact for details

Quality Control

Our 5-(3-Aminothieno[2,3-B]Pyridin-2-Yl)-4-(2-Furylmethyl)-4H-1,2,4-Triazole-3-Thiol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent oxidation and moisture uptake. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %
Residue on Ignition	≤ 0.5 %
Single Unknown Impurity (HPLC)	≤ 1.0 %
Total Impurities (HPLC)	≤ 5.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.