Description

4-Acetyl-8-Benzyl-1-Thia-4,8-Diazaspiro[4.5]Decane-3-Carboxylic Acid Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex spirocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for its role as a key building block in synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• API Synthesis: Serves as a critical building block in the multi-step synthesis of complex target molecules for preclinical and clinical studies.
• Biochemical Tool Compound: Potential use in pharmacological research as a probe to study specific biological pathways and receptor interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and novel heterocycle development.

Basic Information

Item	Details
Product Name	4-Acetyl-8-Benzyl-1-Thia-4,8-Diazaspiro[4.5]Decane-3-Carboxylic Acid Hydrochloride
CAS No.	1030253-99-6
Molecular Formula	C18H23ClN2O3S
Molecular Weight	382.90 g/mol
Synonyms	4-Acetyl-8-benzyl-1-thia-4,8-diazaspiro[4.5]decane-3-carboxylic acid hydrochloride; 1-Thia-4,8-diazaspiro[4.5]decane-3-carboxylic acid, 4-acetyl-8-benzyl-, hydrochloride; 1030253-99-6; 8-Benzyl-4-acetyl-1-thia-4,8-diazaspiro[4.5]decane-3-carboxylic acid HCl; Spiro[4.5]decane-3-carboxylic acid derivative hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Acetyl-8-Benzyl-1-Thia-4,8-Diazaspiro[4.5]Decane-3-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.