Description

Pyridine, 2-[(3S)-3-Pyrrolidinyloxy]-, Dihydrochloride is a high-purity, chiral organic salt of significant interest in advanced pharmaceutical synthesis. This compound matters as a key chiral intermediate or building block, enabling the development of enantiomerically pure active pharmaceutical ingredients (APIs). Pharmaceutical R&D and process chemistry teams need it for the synthesis of complex molecules targeting neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of novel therapeutic agents.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of enantiomerically pure APIs, particularly in central nervous system (CNS) and metabolic disease drug candidates.
• Asymmetric Catalysis Research: Employed as a ligand precursor or a chiral auxiliary in the development of new asymmetric synthetic methodologies.
• Chemical Biology & Medicinal Chemistry: Acts as a versatile scaffold for constructing compound libraries in structure-activity relationship (SAR) studies and high-throughput screening.
• Process Development & Scale-up: Provides a defined, high-quality starting material for optimizing and scaling pharmaceutical manufacturing processes from lab to pilot plant.

Basic Information

Product Name	Pyridine, 2-[(3S)-3-Pyrrolidinyloxy]-, Dihydrochloride
CAS No.	1029715-21-6
Molecular Formula	C9H14N2O·2HCl
Molecular Weight	239.14 g/mol
Synonyms	(S)-2-(3-Pyrrolidinyloxy)pyridine Dihydrochloride; (3S)-2-(3-Pyrrolidinyloxy)pyridine Dihydrochloride; 2-((S)-3-Pyrrolidinyloxy)pyridine Dihydrochloride; 2-[(3S)-3-Pyrrolidinyloxy]pyridine Dihydrochloride; (S)-2-(3-Pyrrolidinoxy)pyridine Dihydrochloride; Pyridine, 2-[(3S)-3-pyrrolidinyloxy]-, hydrochloride (1:2); 1029715-21-6
EINECS	Contact for details

Quality Control

Our Pyridine, 2-[(3S)-3-Pyrrolidinyloxy]-, Dihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.