Description

3-(Difluoromethyl)-5-(4-Methoxyphenyl)-1H-Pyrazole is a specialized pyrazole derivative featuring a difluoromethyl group and a methoxyphenyl substituent, making it a valuable fluorinated building block. This compound is significant for its role in medicinal chemistry and agrochemical research, where its unique structure can impart desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and crop protection industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for developing new drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Research: Used in the discovery and synthesis of novel fungicides and herbicides, leveraging the bioactivity of the pyrazole core.
• Chemical Biology Probe: Acts as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with specific fluorinated properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client R&D programs.

Basic Information

Product Name	3-(Difluoromethyl)-5-(4-Methoxyphenyl)-1H-Pyrazole
CAS No.	1029636-42-7
Molecular Formula	C11H10F2N2O
Molecular Weight	224.21 g/mol
Synonyms	5-(4-Methoxyphenyl)-3-(difluoromethyl)-1H-pyrazole; 3-Difluoromethyl-5-(4-methoxyphenyl)-1H-pyrazole; 1H-Pyrazole, 3-(difluoromethyl)-5-(4-methoxyphenyl)-; 1029636-42-7; 3-(Difluoromethyl)-5-(4-methoxyphenyl)pyrazole
EINECS	Contact for details

Quality Control

Our 3-(Difluoromethyl)-5-(4-Methoxyphenyl)-1H-Pyrazole is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.