Description

3-Chloro-5-Methoxyphenylisocyanide is a specialized aromatic isocyanide building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile ligand and precursor in the development of novel catalysts, pharmaceuticals, and functional materials. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Catalyst Ligand Synthesis: Used in the preparation of specialized isocyanide-based ligands for transition metal catalysis.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides.
• Material Science: Employed in the synthesis of functional polymers and advanced organic frameworks.
• Multicomponent Reactions (MCRs): A valuable reactant in Passerini and Ugi-type reactions for rapid library generation.
• Chemical Biology Probes: Utilized in the design of activity-based probes and bioconjugation reagents.

Basic Information

Product Name	3-Chloro-5-Methoxyphenylisocyanide
CAS No.	1029634-54-5
Molecular Formula	C8H6ClNO
Molecular Weight	167.59 g/mol
Synonyms	1-Chloro-3-isocyano-5-methoxybenzene; 3-Chloro-5-methoxybenzenisocyanide; 5-Methoxy-3-chlorophenyl isocyanide; 3-Chloro-5-methoxyphenyl isonitrile; (3-Chloro-5-methoxyphenyl)isocyanide; Isocyanic acid, (3-chloro-5-methoxyphenyl) ester
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Methoxyphenylisocyanide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if possible. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.