Description

6-Bromo-n-(5-Bromopyridin-2-Yl)Nicotinamide is a high-purity, bifunctionalized heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring two distinct bromine substituents on a nicotinamide-pyridine scaffold, makes it a versatile intermediate for constructing complex pharmacophores. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and other small molecule therapeutic programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science: Acts as a building block for creating functional organic materials, such as ligands for metal-organic frameworks (MOFs) or organic electronic components.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Cross-Coupling Reactions: The bromine atoms provide excellent handles for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse chemical libraries.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) engaged in methodological and synthetic chemistry research.

Basic Information

Item	Detail
Product Name	6-Bromo-n-(5-Bromopyridin-2-Yl)Nicotinamide
CAS No.	1029088-43-4
Molecular Formula	C11H7Br2N3O
Molecular Weight	357.00 g/mol
Synonyms	6-Bromo-N-(5-bromopyridin-2-yl)nicotinamide; 6-Bromo-N-(5-bromo-2-pyridinyl)-3-pyridinecarboxamide; 2-Pyridinecarboxamide, 6-bromo-N-(5-bromo-2-pyridinyl)-; Nicotinamide, 6-bromo-N-(5-bromo-2-pyridinyl)-; 6-Bromo-N-(5-bromopyridin-2-yl)pyridine-3-carboxamide
EINECS	Contact for details

Quality Control

Our 6-Bromo-n-(5-Bromopyridin-2-Yl)Nicotinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality protocols are designed to meet the stringent requirements of GMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.