Description

1H-Pyrrolo[2,3-B]Pyridine-3-Carboxaldehyde, 5-Chloro-1-(Phenylsulfonyl)- is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which serves as a critical precursor for constructing complex pharmacophores and functional materials. This compound is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for the discovery and development of novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, particularly in oncology research, and other small molecule drug candidates.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological pathways and target engagement.
• Academic & Contract Research: Essential for methodological development in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).
• Scale-up & Process Chemistry: Employed in route scouting and optimization for the commercial production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-3-Carboxaldehyde, 5-Chloro-1-(Phenylsulfonyl)-
CAS No.	1029052-72-9
Molecular Formula	C14H9ClN2O3S
Molecular Weight	320.75 g/mol
Synonyms	5-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxaldehyde; 5-Chloro-1-tosyl-7-azaindole-3-carboxaldehyde; 5-Chloro-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde; 5-Chloro-1-(phenylsulfonyl)-7-azaindole-3-carboxaldehyde; 1029052-72-9; 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 5-chloro-1-(phenylsulfonyl)-; 5-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-3-Carboxaldehyde, 5-Chloro-1-(Phenylsulfonyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.