Description

2-Bromo-3-Ethynylpyridine is a high-purity, versatile heterocyclic building block featuring both bromo and ethynyl functional groups. This compound is critical for advanced organic synthesis, particularly in the construction of complex molecular architectures via cross-coupling and click chemistry reactions. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical development, and materials science for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the development of new drug candidates, especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides with specific modes of action.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of conductive polymers, metal-organic frameworks (MOFs), and advanced organic electronic materials.
• Chemical Biology & Bioconjugation: The ethynyl group enables efficient labeling and modification of biomolecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
• Ligand & Catalyst Development: Used to prepare novel pyridine-based ligands for catalysis and coordination chemistry.
• Academic & Industrial R&D: A fundamental research chemical for exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	2-Bromo-3-Ethynylpyridine
CAS No.	1028331-32-9
Molecular Formula	C7H4BrN
Molecular Weight	182.02 g/mol
Synonyms	3-Ethynyl-2-bromopyridine; 2-Bromo-3-ethynylpyridine; Pyridine, 2-bromo-3-ethynyl-; 3-(2-Bromopyridin-3-yl)ethyne; 2-Bromo-3-pyridylacetylene
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-Ethynylpyridine is manufactured and tested under strict quality management protocols to ensure consistent high purity and reliable performance. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.