Description

9-Azadispiro[2.1.2.3]Decane-9-Carboxylic Acid, 4-Oxo-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic and bridged bicyclic architecture. This compound is valued for its role as a critical building block in the synthesis of complex, bioactive molecules, particularly in medicinal chemistry and drug discovery. It is primarily sought after by research institutions and pharmaceutical companies developing novel therapeutics, including protease inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) with complex stereochemistry.
• Medicinal Chemistry Research: Serves as a sophisticated scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Protease Inhibitor Development: Used in the research and development of novel inhibitors targeting specific enzymatic pathways.
• Organic Synthesis Building Block: Employed in academic and industrial labs for constructing challenging spirocyclic and bridged ring systems.
• Process Chemistry & Scale-Up: Supplied for route scouting and optimization during the transition from laboratory to pilot-plant scale production.

Basic Information

Product Name	9-Azadispiro[2.1.2.3]Decane-9-Carboxylic Acid, 4-Oxo-, 1,1-Dimethylethyl Ester
CAS No.	1028320-34-4
Molecular Formula	C14H21NO3
Molecular Weight	251.32 g/mol
Synonyms	tert-Butyl 4-oxo-9-azadispiro[2.1.2.3]decane-9-carboxylate; 9-Boc-9-azadispiro[2.1.2.3]decane-4-one; 1,1-Dimethylethyl 4-oxo-9-azadispiro[2.1.2.3]decane-9-carboxylate; 9-Azadispiro[2.1.2.3]decane-9-carboxylic acid, 4-oxo-, 1,1-dimethylethyl ester; Bicyclo[2.1.2.3]decane derivative; Spirocyclic amine ester
EINECS	Contact for details

Quality Control

Every batch of 9-Azadispiro[2.1.2.3]Decane-9-Carboxylic Acid, 4-Oxo-, 1,1-Dimethylethyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.