Description

5-Iodo-2-(Trifluoromethyl)Pyridin-4-Ol, 4-Hydroxy-5-Iodo-Alpha,Alpha,α-Trifluoro-2-Picoline is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both iodine and trifluoromethyl substituents, makes it an indispensable intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel agrochemicals, pharmaceuticals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, including herbicides and fungicides, where the trifluoromethyl group enhances bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functionalized organic materials, such as liquid crystals or organic semiconductors, due to its halogenated aromatic core.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring precise halogenation and fluorination patterns.

Basic Information

Product Name	5-Iodo-2-(Trifluoromethyl)Pyridin-4-Ol, 4-Hydroxy-5-Iodo-Alpha,Alpha,α-Trifluoro-2-Picoline
CAS No.	1027818-89-8
Molecular Formula	C7H3F3INO
Molecular Weight	288.99 g/mol
Synonyms	4-Hydroxy-5-iodo-2-(trifluoromethyl)pyridine; 5-Iodo-4-hydroxy-2-(trifluoromethyl)pyridine; 4-Hydroxy-5-iodo-α,α,α-trifluoro-2-picoline; 2-(Trifluoromethyl)-5-iodopyridin-4-ol; 5-Iodo-2-trifluoromethyl-4-pyridinol; 4-Pyridinol, 5-iodo-2-(trifluoromethyl)-; 1027818-89-8
EINECS	Contact for details

Quality Control

Every batch of 5-Iodo-2-(Trifluoromethyl)Pyridin-4-Ol is produced and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with industry standards and customer-specific requirements. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.