Description

Di-tert-Butyl 2-Isocyanosuccinate is a high-purity, protected isocyanosuccinate derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a reactive isocyano group adjacent to a protected ester functionality, enabling the construction of complex heterocycles and peptidomimetics. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and specialized fine chemicals.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of heterocyclic compounds, β-lactams, and other nitrogen-containing bioactive molecules.
• Peptidomimetic Research: Used to introduce isocyano groups into peptide backbones for the development of novel protease inhibitors and receptor modulators.
• Agrochemical Synthesis: Building block for creating new classes of herbicides, fungicides, and insecticides with unique modes of action.
• Material Science: Potential monomer or cross-linking agent in the development of specialized polymers and resins.
• Academic & R&D: Valuable reagent for methodological development in organic chemistry, including multicomponent reactions and catalysis studies.

Basic Information

Product Name	Di-tert-Butyl 2-Isocyanosuccinate
CAS No.	1027757-05-6
Molecular Formula	C13H21NO4
Molecular Weight	255.31 g/mol
Synonyms	2-Isocyano-2,4-di-tert-butoxy-4-oxobutanoic acid; Di-tert-butyl 2-isocyano-2,4-dioxobutanoate; 2-Isocyanosuccinic acid di-tert-butyl ester; Di-tert-butyl isocyanosuccinate; 2,4-Di-O-tert-butyl 2-isocyanosuccinate; Butanedioic acid, 2-isocyano-, 1,4-di-tert-butyl ester; DTBSI
EINECS	Contact for details

Quality Control

Our Di-tert-Butyl 2-Isocyanosuccinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, guaranteeing traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.