Description

4-Chloromethyl-2-Trifluoromethyl-Pyridine is a high-value, multi-functional heterocyclic building block characterized by its reactive chloromethyl group and electron-withdrawing trifluoromethyl substituent. This compound is essential for facilitating rapid and efficient molecular diversification in advanced synthetic workflows, offering chemists a versatile handle for constructing complex target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and intermediates.

Application

This specialized pyridine derivative serves as a critical intermediate in several high-tech chemical synthesis domains:

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing candidates with improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel pyridine-based ligands used in catalysis and material science.
• Functional Material Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for fine chemical and custom synthesis houses serving the life sciences industry.

Basic Information

Item	Details
Product Name	4-Chloromethyl-2-Trifluoromethyl-Pyridine
CAS No.	1027545-48-7
Molecular Formula	C7H5ClF3N
Molecular Weight	195.57 g/mol
Synonyms	2-(Trifluoromethyl)-4-(chloromethyl)pyridine; 4-(Chloromethyl)-2-(trifluoromethyl)pyridine; 2-Trifluoromethyl-4-chloromethylpyridine; Pyridine, 4-(chloromethyl)-2-(trifluoromethyl)-; 4-Chloromethyl-2-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our production of 4-Chloromethyl-2-Trifluoromethyl-Pyridine adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including HPLC, GC, and NMR to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.