Description

2,5-Dioxopyrrolidin-1-Yl 3-Methoxypropanoate is a specialized active ester reagent widely used in organic synthesis and bioconjugation chemistry. Its primary value lies in its high reactivity as an acylating agent, enabling efficient and selective coupling reactions under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and life science industries, particularly for the synthesis of complex molecules, peptide modifications, and the development of novel drug conjugates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs) and prodrugs.
• Bioconjugation Reagent: Used for labeling proteins, antibodies, and peptides with fluorescent dyes, drugs, or other functional molecules.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent in the production of specialty polymers and hydrogels.
• Peptide Synthesis: Facilitates the formation of amide bonds in solid-phase and solution-phase peptide synthesis.
• Agrochemical Synthesis: Employed in the manufacturing of advanced crop protection agents and herbicides.
• Material Science: Used to modify surface properties and create functionalized materials for diagnostic and sensor applications.

Basic Information

Item	Detail
Product Name	2,5-Dioxopyrrolidin-1-Yl 3-Methoxypropanoate
CAS No.	1027371-75-0
Molecular Formula	C8H11NO5
Molecular Weight	201.18 g/mol
Synonyms	3-Methoxypropanoic Acid N-Hydroxysuccinimide Ester; 3-Methoxypropionic Acid N-Succinimidyl Ester; N-Succinimidyl 3-Methoxypropionate; NHS Ester of 3-Methoxypropionic Acid; 1-[(3-Methoxypropanoyl)oxy]-2,5-pyrrolidinedione; 2,5-Dioxo-1-pyrrolidinyl 3-methoxypropanoate; SMP Ester
EINECS	Contact for details

Quality Control

Our 2,5-Dioxopyrrolidin-1-Yl 3-Methoxypropanoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.