Description

1-(2,6-Bis-Trifluoromethyl-Pyridin-3-Yl)-Ethanone is a high-value trifluoromethylated pyridine derivative, a key building block in advanced organic synthesis. Its structure, featuring electron-withdrawing trifluoromethyl groups, is engineered to impart enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with improved properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Serves as a key scaffold for developing new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Material Science Research: Used in the development of advanced organic electronic materials, including ligands for catalysts and components for organic light-emitting diodes (OLEDs).
• Fluorine Chemistry Building Block: An important reagent for introducing the trifluoromethylpyridine moiety into complex molecules, facilitating structure-activity relationship (SAR) studies.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and custom synthesis facilities for proprietary client projects and library synthesis.

Basic Information

Product Name	1-(2,6-Bis-Trifluoromethyl-Pyridin-3-Yl)-Ethanone
CAS No.	1027369-24-9
Molecular Formula	C10H5F6NO
Molecular Weight	269.15 g/mol
Synonyms	3-Acetyl-2,6-bis(trifluoromethyl)pyridine; 2,6-Bis(trifluoromethyl)-3-acetylpyridine; 1-[2,6-Bis(trifluoromethyl)pyridin-3-yl]ethanone; Ethanone, 1-[2,6-bis(trifluoromethyl)-3-pyridinyl]-; 3-Acetyl-2,6-di(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our 1-(2,6-Bis-Trifluoromethyl-Pyridin-3-Yl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.