Description

3H-Imidazo[4,5-B]Pyridine-3-Carboxylic Acid, 1,2-Dihydro-2-Oxo-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting innovative therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting kinase inhibition and other enzymatic pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in drug discovery programs.
• Bioconjugate Development: Serves as a reactive handle for creating bioconjugates or antibody-drug conjugates (ADCs) due to its functionalized ester group.
• Agrochemical Synthesis: Employed in the research and development of advanced agrochemicals and plant protection agents.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in heterocyclic chemistry and organic synthesis methodologies.

Basic Information

Product Name	3H-Imidazo[4,5-B]Pyridine-3-Carboxylic Acid, 1,2-Dihydro-2-Oxo-, 1,1-Dimethylethyl Ester
CAS No.	1027159-01-8
Molecular Formula	C13H15N3O3
Molecular Weight	261.28 g/mol
Synonyms	tert-Butyl 2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridine-3-carboxylate; 1,1-Dimethylethyl 1,2-dihydro-2-oxo-3H-imidazo[4,5-b]pyridine-3-carboxylate; 3H-Imidazo[4,5-b]pyridine-3-carboxylic acid, 1,2-dihydro-2-oxo-, 1,1-dimethylethyl ester; 2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridine-3-carboxylic acid tert-butyl ester; tert-Butyl 2-oxo-1,2-dihydro-3H-imidazo[4,5-b]pyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our production of 3H-Imidazo[4,5-B]Pyridine-3-Carboxylic Acid, 1,2-Dihydro-2-Oxo-, 1,1-Dimethylethyl Ester adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research-grade and pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.