Description

2,5,7-Triazaspiro[3.4]Octane-6,8-Dione Hydrochloride is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic heterocycle class. This compound is valued for its unique three-dimensional structure, which makes it a critical building block in modern medicinal chemistry for developing novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of new drug candidates, particularly in areas requiring complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Proteolysis Targeting Chimera (PROTAC) Development: Used in the construction of linker molecules and warhead conjugates due to its spirocyclic rigidity and functional handles.
• Chemical Biology Probes: Employed in the development of tool compounds for studying enzyme function and biological pathways.
• Agrochemical Research: Potential intermediate in the discovery of new crop protection agents with novel modes of action.
• Material Science: Exploration as a monomer or additive for creating polymers with specific thermal or mechanical properties.

Basic Information

Product Name	2,5,7-Triazaspiro[3.4]Octane-6,8-Dione Hydrochloride
CAS No.	1026796-27-9
Molecular Formula	C6H8N3O2·HCl
Molecular Weight	191.61 g/mol (Free base: 155.15 g/mol)
Synonyms	2,5,7-Triazaspiro[3.4]octane-6,8-dione hydrochloride; 6,8-Dioxo-2,5,7-triazaspiro[3.4]octane hydrochloride; 2,5,7-Triazaspiro[3.4]octane-6,8-dione HCl; 1026796-27-9; Spiro[3.4]octane-6,8-dione, 2,5,7-triaza-, hydrochloride; 6,8-Dihydroxy-2,5,7-triazaspiro[3.4]octane hydrochloride (tautomeric form)
EINECS	Contact for details

Quality Control

Every batch of 2,5,7-Triazaspiro[3.4]Octane-6,8-Dione Hydrochloride is manufactured under a quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets specifications suitable for research and development use. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.