Description

Methyl 2-Bromo-5-(Trifluoromethyl)Benzoate is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. This compound is valued for its unique trifluoromethyl and bromo substituents, which enable precise molecular modifications in complex chemical architectures. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethylated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the bromine atom serves as a versatile handle for further functionalization.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials that benefit from the electronic properties of the trifluoromethyl group.
• Cross-Coupling Reactions: Serves as a competent substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) for constructing complex biaryl structures.
• Fluorine Chemistry: An important reagent for introducing fluorine-containing motifs into target molecules, a critical strategy in modern medicinal and agrochemical design.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Item	Details
Product Name	Methyl 2-Bromo-5-(Trifluoromethyl)Benzoate
CAS No.	1026355-57-6
Molecular Formula	C9H6BrF3O2
Molecular Weight	283.04 g/mol
Synonyms	2-Bromo-5-(trifluoromethyl)benzoic acid methyl ester; Methyl 2-bromo-α,α,α-trifluoro-m-toluate; Benzoic acid, 2-bromo-5-(trifluoromethyl)-, methyl ester; Methyl 2-bromo-5-trifluoromethylbenzoate; 2-Bromo-5-trifluoromethylbenzoic acid methyl ester; m-Trifluoromethyl-2-bromobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Bromo-5-(Trifluoromethyl)Benzoate is produced and tested under a strict quality management system. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. A Certificate of Analysis (COA) detailing identity, purity (typically by HPLC or GC), and impurity profiles is provided with each shipment to ensure it meets your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.