Description

2-(4-(4-(4-(Diphenylmethylene)Piperidin-1-Yl)Butanoyl)Phenyl)-2-Methylpropanoic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex piperidine-based structure. This compound is of significant commercial value for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought after by research institutions, custom synthesis organizations, and pharmaceutical companies engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, especially for central nervous system (CNS) and anti-inflammatory targets.
• Custom Synthesis & Contract Manufacturing: Serves as a critical starting material or intermediate for contract research organizations (CROs) and CDMOs offering bespoke synthesis services.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its unique diphenylmethylene piperidine moiety.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	2-(4-(4-(4-(Diphenylmethylene)Piperidin-1-Yl)Butanoyl)Phenyl)-2-Methylpropanoic Acid Methyl Ester
CAS No.	1025909-08-3
Molecular Formula	C35H39NO3
Molecular Weight	521.69 g/mol
Synonyms	Methyl 2-[4-[4-[4-(diphenylmethylidene)piperidin-1-yl]butanoyl]phenyl]-2-methylpropanoate; 2-Methyl-2-[4-[4-[4-(benzhydrylidene)piperidin-1-yl]-1-oxobutyl]phenyl]propanoic acid methyl ester; CAS 1025909-08-3; 2-(4-(4-(4-(Diphenylmethylene)-1-piperidinyl)-1-oxobutyl)phenyl)-2-methylpropanoic acid methyl ester; Propanoic acid, 2-methyl-2-[4-[4-[4-(phenylmethylene)phenyl]-1-piperidinyl]-1-oxobutyl]phenyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our 2-(4-(4-(4-(Diphenylmethylene)Piperidin-1-Yl)Butanoyl)Phenyl)-2-Methylpropanoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with custom purity grades and documentation tailored to cGMP, ICH Q7, and other relevant regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.