Description

(9S,13S)-Tri-tert-Butyl 3,11-Dioxo-1-Phenyl-2-Oxa-4,10,12-Triazapentadecane-9,13,15-Tricarboxylate CAS NO 1025796-30-8 is a sophisticated, multi-functional organic compound featuring a complex peptide-like backbone with tert-butyl ester protecting groups. This molecule is of significant value as a key chiral building block and advanced intermediate in the synthesis of complex pharmaceuticals and bioactive compounds. It is primarily needed by research institutions and pharmaceutical development companies engaged in the discovery and process development of new therapeutic agents, particularly those targeting protease-related pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral scaffold in the multi-step synthesis of novel active pharmaceutical ingredients (APIs), especially for protease inhibitors.
• Peptidomimetic Research: Used in medicinal chemistry to design and synthesize peptide analogs with enhanced metabolic stability and bioavailability.
• Chemical Biology Probe Development: Acts as a precursor for creating labeled or tagged molecules to study enzyme function and protein-protein interactions.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of target drug candidates.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity, complex intermediates.
• Academic Research: Utilized in university and institutional labs for methodological development in asymmetric synthesis and protecting group chemistry.

Basic Information

Product Name	(9S,13S)-Tri-tert-Butyl 3,11-Dioxo-1-Phenyl-2-Oxa-4,10,12-Triazapentadecane-9,13,15-Tricarboxylate
CAS No.	1025796-30-8
Molecular Formula	C33H51N3O9
Molecular Weight	633.78 g/mol
Synonyms	Tri-tert-butyl (9S,13S)-3,11-dioxo-1-phenyl-2-oxa-4,10,12-triazapentadecane-9,13,15-tricarboxylate; (9S,13S)-1-Phenyl-2-oxa-4,10,12-triazapentadecane-3,11-dione-9,13,15-tricarboxylic acid tri-tert-butyl ester; Tri-tert-butyl N-[(2S)-1-[[(2S)-5-(tert-butoxy)-1-(phenylamino)-1,5-dioxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-L-glutamate; Boc-Protected Peptidomimetic Intermediate; CAS 1025796-30-8
EINECS	Contact for details

Quality Control

Our (9S,13S)-Tri-tert-Butyl 3,11-Dioxo-1-Phenyl-2-Oxa-4,10,12-Triazapentadecane-9,13,15-Tricarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and chiral integrity, utilizing techniques such as HPLC, NMR, and MS. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet client-specific requirements or GMP standards for advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.