Description

1H-3-Chloro-Pyrrolo[2,3-B]Pyridine-5-Boronic Acid Pinacol Ester CAS NO 1025719-17-8 is a high-purity, heterocyclic boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing novel drug candidates, especially in kinase inhibitor and oncology research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Serves as a precursor for creating organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and molecular probes for biological target identification.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific heterocyclic frameworks.
• Academic & R&D Laboratories: Enables methodological development and exploration of new C-C bond-forming reactions in academic settings.

Basic Information

Product Name	1H-3-Chloro-Pyrrolo[2,3-B]Pyridine-5-Boronic Acid Pinacol Ester
CAS No.	1025719-17-8
Molecular Formula	C13H16BClN2O2
Molecular Weight	278.54 g/mol
Synonyms	3-Chloro-1H-pyrrolo[2,3-b]pyridine-5-boronic acid pinacol ester; 3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-5-boronic acid, 3-chloro-, 1,1,1',1'-tetramethyl-2,2'-bi-1,3,2-benzodioxaborole ester; 1025719-17-8; 3-Chloro-1H-pyrrolo[2,3-b]pyridin-5-ylboronic acid pinacol ester.
EINECS	Contact for details

Quality Control

Our 1H-3-Chloro-Pyrrolo[2,3-B]Pyridine-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.