Description

1-Pyrrolidinecarboxylic Acid, 3-(4-Pyridinyl)-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in medicinal chemistry. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors for the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive compounds.
• API Development: Used in the process development and scale-up manufacturing of Active Pharmaceutical Ingredients (APIs).
• Chemical Synthesis: Employed in organic synthesis as a protected amino acid derivative for constructing peptidomimetics and other nitrogen-containing heterocycles.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process optimization for pharmaceutical clients.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and drug discovery methodologies.

Basic Information

Item	Details
Product Name	1-Pyrrolidinecarboxylic Acid, 3-(4-Pyridinyl)-, 1,1-Dimethylethyl Ester
CAS No.	1024590-32-6
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	tert-Butyl 3-(pyridin-4-yl)pyrrolidine-1-carboxylate; 3-(4-Pyridinyl)-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester; 4-(1-Boc-pyrrolidin-3-yl)pyridine; Boc-3-(4-Pyridyl)pyrrolidine; 1-Boc-3-(4-Pyridyl)pyrrolidine; 3-(4-Pyridyl)pyrrolidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarboxylic Acid, 3-(4-Pyridinyl)-, 1,1-Dimethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.