Description

2-Chloro(3-Pyridyl) 4-(5-Chloro-2-Methylphenyl)Piperazinyl Ketone is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in medicinal chemistry research and development, particularly for its role as a key building block in synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought by R&D teams and process chemists in the pharmaceutical and biotechnology industries for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• API Development: Serves in the process development and scale-up of new chemical entities (NCEs), particularly those with piperazine and pyridine pharmacophores.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical market.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	2-Chloro(3-Pyridyl) 4-(5-Chloro-2-Methylphenyl)Piperazinyl Ketone
CAS No.	1024496-60-3
Molecular Formula	C17H17Cl2N3O
Molecular Weight	350.24 g/mol
Synonyms	2-Chloro-3-pyridyl 4-(5-chloro-2-methylphenyl)piperazine-1-carboxylate; 1-(5-Chloro-2-methylphenyl)-4-[(2-chloropyridin-3-yl)carbonyl]piperazine; 4-(5-Chloro-2-methylphenyl)-1-[(2-chloro-3-pyridinyl)carbonyl]piperazine; 1024496-60-3; (2-Chloropyridin-3-yl)[4-(5-chloro-2-methylphenyl)piperazin-1-yl]methanone
EINECS	Contact for details

Quality Control

Our 2-Chloro(3-Pyridyl) 4-(5-Chloro-2-Methylphenyl)Piperazinyl Ketone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container sealed to protect this moisture-sensitive material from humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.