Description

4-Bromo-2-Methyl-1-Phenyl-3-(2-Pyridylthiomethyl)-3-Pyrazolin-5-One is a specialized heterocyclic organic compound featuring a pyrazolone core substituted with bromo, phenyl, and pyridylthiomethyl groups. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, particularly those targeting specific enzyme inhibition or receptor modulation.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in therapeutic areas requiring complex heterocyclic scaffolds.
• Medicinal Chemistry Research: Serves as a versatile building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Used in the research and development of new pesticides and herbicides, leveraging its bioactive pyrazolone structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target identification.
• Organic Synthesis Reagent: Acts as a specialized reagent for introducing the 3-pyrazolin-5-one moiety into more complex molecular architectures.

Basic Information

Item	Details
Product Name	4-Bromo-2-Methyl-1-Phenyl-3-(2-Pyridylthiomethyl)-3-Pyrazolin-5-One
CAS No.	1024324-23-9
Molecular Formula	C₁₆H₁₄BrN₃OS
Molecular Weight	376.27 g/mol
Synonyms	4-Bromo-2-methyl-1-phenyl-3-[(pyridin-2-ylsulfanyl)methyl]-1H-pyrazol-5(4H)-one; 4-Bromo-2-methyl-1-phenyl-3-(pyridin-2-ylthiomethyl)pyrazol-5-one; 3-Pyrazolin-5-one, 4-bromo-2-methyl-1-phenyl-3-(2-pyridinylthiomethyl)-; 4-Bromo-2-methyl-1-phenyl-3-((pyridin-2-ylthio)methyl)-1H-pyrazol-5(4H)-one
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Methyl-1-Phenyl-3-(2-Pyridylthiomethyl)-3-Pyrazolin-5-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports your research and development needs with reliable, high-purity materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.