Description

6-Oxospiro[3.3]heptane-2,2-dicarboxylic acid (X4473) is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic and dicarboxylic acid structure. This compound is valued for its role as a critical building block in the synthesis of complex, bioactive molecules, particularly in medicinal chemistry and drug discovery. It is primarily sought by research institutions and pharmaceutical companies engaged in developing novel therapeutic agents, including protease inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Medicinal Chemistry: Serves as a versatile scaffold for constructing complex molecular architectures with potential biological activity.
• Protease Inhibitor Research: Used in the synthesis of compounds designed to modulate protease enzyme activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing spirocyclic compounds and exploring novel chemical space.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	6-Oxospiro[3.3]heptane-2,2-dicarboxylic Acid (X4473)
CAS No.	1023814-92-7
Molecular Formula	C9H10O5
Molecular Weight	198.17 g/mol
Synonyms	2,2-Dicarboxy-6-oxospiro[3.3]heptane; 6-Oxospiro[3.3]heptane-2,2-dicarboxylic acid; Spiro[3.3]heptane-2,2-dicarboxylic acid, 6-oxo-; X4473; 1023814-92-7; 6-Oxospiro[3.3]heptane-2,2-dicarboxylate; 2,2-Bis(carboxy)-6-oxospiro[3.3]heptane
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced intermediates. Each batch is analyzed using validated methods including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all critical quality attributes are available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.