Description

5,6,7,8-Tetrahydro-[1,8]Naphthyridine-3-Bromide is a high-purity, functionalized naphthyridine derivative, serving as a critical advanced intermediate in modern organic synthesis. Its core value lies in enabling the construction of complex nitrogen-containing heterocycles, which are foundational scaffolds in pharmaceutical discovery and material science. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in developing kinase inhibitors, receptor modulators, and other biologically active molecules.
• Agrochemical Research: Used in creating novel active ingredients for crop protection products, leveraging its heterocyclic structure for enhanced bioactivity.
• Ligand Synthesis: Serves as a precursor for chelating ligands in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the development of organic electronic materials, dyes, and photoactive compounds due to its conjugated system.
• Chemical Biology Probes: Utilized as a core structure for designing molecular probes and tools to study biological processes.
• Academic & Contract Research: A valuable reagent for methodology development and exploratory synthesis in academic and industrial R&D laboratories.

Basic Information

Product Name	5,6,7,8-Tetrahydro-[1,8]Naphthyridine-3-Bromide
CAS No.	1023813-80-0
Molecular Formula	C9H11BrN2
Molecular Weight	227.10 g/mol
Synonyms	3-Bromo-5,6,7,8-tetrahydro-1,8-naphthyridine; 5,6,7,8-Tetrahydro-1,8-naphthyridin-3-yl bromide; 3-Bromo-5,6,7,8-tetrahydro[1,8]naphthyridine; Tetrahydro[1,8]naphthyridine-3-bromide; 1,8-Naphthyridine, 3-bromo-5,6,7,8-tetrahydro-; 3-Bromotetrahydro-1,8-naphthyridine
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro-[1,8]Naphthyridine-3-Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates for GLP and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.