Description

6-Methyl-5-Trifluoromethyl-Pyridin-2-Ylamine is a high-value pyridine derivative featuring a trifluoromethyl group, a key structural motif prized for its ability to modulate the physicochemical properties of advanced molecules. This compound serves as a critical building block in the synthesis of complex agrochemicals and pharmaceuticals, where its unique fluorine-substituted heterocyclic core imparts enhanced metabolic stability and bioavailability. It is primarily sought by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in areas targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Intermediate: Used in the synthesis of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or fluorinated polymers, due to its electron-withdrawing characteristics.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring fluorinated pyridine scaffolds.

Basic Information

Product Name	6-Methyl-5-Trifluoromethyl-Pyridin-2-Ylamine
CAS No.	1023813-33-3
Molecular Formula	C8H7F3N2
Molecular Weight	188.15 g/mol
Synonyms	2-Amino-6-methyl-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-6-methylpyridin-2-amine; 6-Methyl-5-(trifluoromethyl)pyridin-2-amine; 2-Pyridinamine, 6-methyl-5-(trifluoromethyl)-; 6-Methyl-5-trifluoromethyl-2-pyridinamine; 5-Trifluoromethyl-6-methyl-pyridin-2-ylamine
EINECS	Contact for details

Quality Control

Our production of 6-Methyl-5-Trifluoromethyl-Pyridin-2-Ylamine adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is fully characterized and undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We operate under a cGMP-compliant quality management system suitable for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.