Description

1-Piperazinecarboxylic Acid, 4-(2-Amino-3-Pyridinyl)-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperazine-pyridine hybrid structure. This compound is of significant commercial value for its critical role in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought after by research institutions and manufacturers in the global pharmaceutical and biotechnology sectors for the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drugs, particularly those targeting central nervous system (CNS) disorders and oncology.
• API Synthesis: Used in the multi-step production of complex Active Pharmaceutical Ingredients (APIs) that incorporate piperazine and aminopyridine pharmacophores.
• Medicinal Chemistry Research: Serves as a versatile scaffold in drug discovery and lead optimization programs for structure-activity relationship (SAR) studies.
• Contract Manufacturing (CDMO): Supplied to Contract Development and Manufacturing Organizations for cGMP production of clinical trial materials and commercial APIs.
• Bioconjugation & Probe Development: The amino and ester functional groups allow for further derivatization, making it useful for creating biochemical probes and labeled compounds.

Basic Information

Product Name	1-Piperazinecarboxylic Acid, 4-(2-Amino-3-Pyridinyl)-, 1,1-Dimethylethyl Ester
CAS No.	1023594-49-1
Molecular Formula	C14H22N4O2
Molecular Weight	278.35 g/mol
Synonyms	tert-Butyl 4-(2-amino-3-pyridinyl)piperazine-1-carboxylate; 4-(2-Aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester; 1-Boc-4-(2-amino-3-pyridyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(2-amino-3-pyridinyl)piperazine; 1023594-49-1; 4-(2-Aminopyridin-3-yl)-N-Boc-piperazine
EINECS	Contact for details

Quality Control

Our production of 1-Piperazinecarboxylic Acid, 4-(2-Amino-3-Pyridinyl)-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity suitable for pharmaceutical R&D and cGMP applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.