Description

2-(4-(3-Chloro-5-(Trifluoromethyl)-2-Pyridyloxy)Phenyl)-1,2,3-Trihydroquinazolin-4-One is a high-purity, advanced pharmaceutical intermediate critical for modern drug discovery and development. This compound is valued for its complex heterocyclic structure, which serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers focused on developing new therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates and target molecules.
• Agrochemical Research: Serves as a key structural component in the development of new pesticides and herbicides, leveraging its pyridine and quinazolinone motifs.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex heterocyclic systems for biological screening.
• Biochemical Research: Employed in the study of enzyme inhibitors and receptor ligands due to its specific pharmacophore.
• Material Science Exploration: Investigated for potential applications in creating specialty chemicals and functional materials.

Basic Information

Product Name	2-(4-(3-Chloro-5-(Trifluoromethyl)-2-Pyridyloxy)Phenyl)-1,2,3-Trihydroquinazolin-4-One
CAS No.	1023488-59-6
Molecular Formula	C20H12ClF3N3O2
Molecular Weight	418.78 g/mol
Synonyms	2-[4-[(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy]phenyl]-1,2,3,4-tetrahydroquinazolin-4-one; 2-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-1,2,3,4-tetrahydro-4-quinazolinone; CAS 1023488-59-6; 1,2,3,4-Tetrahydro-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]-4-quinazolinone; 2-(4-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-1,2,3,4-tetrahydroquinazolin-4-one
EINECS	Contact for details

Quality Control

Our 2-(4-(3-Chloro-5-(Trifluoromethyl)-2-Pyridyloxy)Phenyl)-1,2,3-Trihydroquinazolin-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.