Description

4-Fluoro-4-Methylpiperidine Hydrochloride is a high-purity, functionalized piperidine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic incorporation of fluorine and a basic amine, enabling the modulation of lipophilicity, metabolic stability, and binding affinity in target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key synthon for the development of central nervous system (CNS) active drugs, enzyme inhibitors, and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances bioactivity and environmental persistence.
• Chemical Biology & Medicinal Chemistry: Employed as a versatile scaffold for constructing compound libraries for high-throughput screening and lead optimization.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or functional additive for specialty polymers with tailored properties.

Basic Information

Product Name	4-Fluoro-4-Methylpiperidine Hydrochloride
CAS No.	1023305-87-4
Molecular Formula	C6H13ClFN
Molecular Weight	153.63 g/mol
Synonyms	4-Fluoro-4-methylpiperidine HCl; 4-Fluoro-4-methylpiperidine hydrochloride; 4-Methyl-4-fluoropiperidine hydrochloride; Piperidine, 4-fluoro-4-methyl-, hydrochloride (1:1); 4-Fluoro-4-methylpiperidinium chloride
EINECS	Contact for details

Quality Control

Our 4-Fluoro-4-Methylpiperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.