Description

3-(5-Bromopyridine)Propanoic Acid is a high-purity brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromine-substituted pyridine motifs into their target structures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Building block for organic electronic materials, such as those used in OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	3-(5-Bromopyridine)Propanoic Acid
CAS No.	1022128-98-8
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	5-Bromo-3-pyridinepropanoic Acid; 3-(5-Bromo-3-pyridyl)propanoic Acid; 3-(5-Bromopyridin-3-yl)propanoic Acid; β-(5-Bromo-3-pyridyl)propionic Acid; 5-Bromonicotinylpropionic Acid; 1022128-98-8; 3-Pyridinepropanoic acid, 5-bromo-
EINECS	Contact for details

Quality Control

Every batch of 3-(5-Bromopyridine)Propanoic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the stringent requirements of our global clientele. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.