Description

N,N'-Bis[2-(Chloroacetamido)Ethyl]-N,N'-Dimethylrhodamine is a specialized, bifunctional reactive dye derivative designed for advanced bioconjugation and labeling applications. Its core value lies in its ability to serve as a highly efficient cross-linking agent, enabling the covalent attachment of fluorescent rhodamine tags to target biomolecules via its chloroacetamido reactive groups. This compound is essential for researchers and manufacturers in the fields of biochemical research, diagnostic assay development, and pharmaceutical analysis, where precise and stable fluorescent labeling is required.

Application

• Fluorescent Probe Synthesis: A key precursor for creating custom fluorescent probes and tags for bioimaging.
• Protein & Antibody Labeling: Used to covalently conjugate the rhodamine fluorophore to proteins, antibodies, and other peptides for detection and tracking.
• Bioconjugation Chemistry: Serves as a cross-linker in the development of diagnostic kits and biosensors.
• Cell Biology Research: Facilitates the fluorescent labeling of cellular components for microscopy and flow cytometry.
• Material Science: Potential use in the surface functionalization of nanoparticles with fluorescent markers.
• Chemical Biology: Employed in activity-based protein profiling and other advanced research methodologies.

Basic Information

Product Name	N,N'-Bis[2-(Chloroacetamido)Ethyl]-N,N'-Dimethylrhodamine
CAS No.	1022050-89-0
Molecular Formula	C31H32Cl2N4O5
Molecular Weight	611.52 g/mol
Synonyms	N,N'-Bis(2-chloroacetamidoethyl)-N,N'-dimethylrhodamine; BCAE-DMRhodamine; Rhodamine-based bis-chloroacetamide; Tetramethylrhodamine bis-chloroacetamide; Reactive Rhodamine 6G derivative; 5(6)-TAMRA bis-chloroacetamide; Fluorescent crosslinker 1022050-89-0
EINECS	Contact for details

Quality Control

Our N,N'-Bis[2-(Chloroacetamido)Ethyl]-N,N'-Dimethylrhodamine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support compliance with ISO and GMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light). Keep the container tightly sealed in a desiccated environment to protect from moisture.

Specification

Item	Specification
Appearance	Dark red to purple solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Loss on Drying	≤ 1.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.