Description

3H-Imidazo[4,5-B]Pyridine-3-Carboxylic Acid, 6-Bromo-1,2-Dihydro-2-Oxo-, 1,1-Dimethylethyl Ester is a high-value brominated heterocyclic building block, specifically designed for advanced pharmaceutical and agrochemical research and development. This compound is critical for medicinal chemists seeking to introduce the imidazopyridine scaffold, a privileged structure known for modulating a wide range of biological targets. It is primarily utilized by R&D teams in the pharmaceutical, biotechnology, and fine chemical synthesis sectors for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of potential drug candidates targeting kinases, GPCRs, and other enzymes.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Employed in the research and synthesis of novel herbicides, fungicides, or insecticides with the imidazopyridine core.
• Chemical Biology Probes: Acts as a building block for creating molecular probes to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical manufacturers for producing bespoke compounds and advanced intermediates.
• Academic Research: Used in university and institutional labs for heterocyclic chemistry studies and the development of new synthetic methodologies.

Basic Information

Item	Detail
Product Name	3H-Imidazo[4,5-B]Pyridine-3-Carboxylic Acid, 6-Bromo-1,2-Dihydro-2-Oxo-, 1,1-Dimethylethyl Ester
CAS No.	1021919-65-2
Molecular Formula	C13H14BrN3O3
Molecular Weight	340.18 g/mol
Synonyms	tert-Butyl 6-bromo-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridine-3-carboxylate; 6-Bromo-1,2-dihydro-2-oxo-3H-imidazo[4,5-b]pyridine-3-carboxylic acid 1,1-dimethylethyl ester; 6-Bromo-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridine-3-carboxylic acid tert-butyl ester; 1021919-65-2; tert-Butyl 6-bromo-2-oxo-1,3-dihydroimidazo[4,5-b]pyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our 3H-Imidazo[4,5-B]Pyridine-3-Carboxylic Acid, 6-Bromo-1,2-Dihydro-2-Oxo-, 1,1-Dimethylethyl Ester is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.