Description

(S)-Methyl 2-Hydroxy-3-(4-Nitrophenyl)Propanoate CAS NO 1021692-54-5 is a high-purity chiral building block and synthetic intermediate of significant commercial and research interest. Its value lies in its defined stereochemistry and functional groups, which are critical for constructing complex molecules with specific biological activity. This compound is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Key chiral intermediate in the asymmetric synthesis of pharmaceutical candidates.
• Building block for the development of protease inhibitors and other enzyme-targeted therapeutics.
• Precursor in the research and production of agrochemicals requiring specific stereoisomers for enhanced efficacy.
• Starting material for the synthesis of liquid crystals and advanced organic electronic materials.
• Versatile reagent in methodology development for organic and medicinal chemistry.
• Intermediate for producing custom fine chemicals and specialty compounds under cGMP conditions.

Basic Information

Item	Details
Product Name	(S)-Methyl 2-Hydroxy-3-(4-Nitrophenyl)Propanoate
CAS No.	1021692-54-5
Molecular Formula	C10H11NO5
Molecular Weight	225.20 g/mol
Synonyms	(S)-Methyl 2-Hydroxy-3-(4-nitrophenyl)propionate; Methyl (2S)-2-hydroxy-3-(4-nitrophenyl)propanoate; (S)-(-)-Methyl 2-hydroxy-3-(4-nitrophenyl)propanoate; (S)-Methyl 3-(4-nitrophenyl)-2-hydroxypropanoate; (S)-2-Hydroxy-3-(4-nitrophenyl)propionic acid methyl ester; (S)-HMPA Methyl Ester; (S)-Methyl 4-Nitrobenzylglycidate (hydrolyzed form)
EINECS	Contact for details

Quality Control

Our (S)-Methyl 2-Hydroxy-3-(4-Nitrophenyl)Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.