Description

4-Pyridinecarboxylic Acid, 2-(1,1-Difluoroethyl)- is a specialized fluorinated pyridine derivative, serving as a high-value building block in advanced organic synthesis. Its unique structure, featuring a difluoroethyl substituent, makes it a critical intermediate for introducing fluorine atoms into target molecules, thereby modulating their physicochemical and biological properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology, CNS, and antiviral research.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where fluorine incorporation enhances stability and bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing novel ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of fluorinated organic materials, including liquid crystals and electronic chemicals.
• Chemical Biology Probes: Useful for creating fluorinated probes and tags for studying biological mechanisms and diagnostics.

Basic Information

Product Name	4-Pyridinecarboxylic Acid, 2-(1,1-Difluoroethyl)-
CAS No.	1021535-48-7
Molecular Formula	C8H7F2NO2
Molecular Weight	187.14 g/mol
Synonyms	2-(1,1-Difluoroethyl)isonicotinic Acid; 2-(1,1-Difluoroethyl)-4-pyridinecarboxylic Acid; 2-(1,1-Difluoroethyl)pyridine-4-carboxylic Acid; 4-Carboxy-2-(1,1-difluoroethyl)pyridine; Isonicotinic Acid, 2-(1,1-difluoroethyl)-; 1021535-48-7
EINECS	Contact for details

Quality Control

We supply 4-Pyridinecarboxylic Acid, 2-(1,1-Difluoroethyl)- in high-purity grades suitable for research and commercial-scale synthesis. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to cGMP principles for production and quality management where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.