Description

(+/-)-2-(3-Pyridinyl)-1-Azabicyclo(2.2.2)Octane Dihydrochloride CAS NO 1021418-53-0 is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in medicinal chemistry and neuroscience research. It is primarily sought by R&D laboratories, academic institutions, and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Neuroscience & Neuropharmacology: Serves as a research tool for investigating nicotinic acetylcholine receptor (nAChR) interactions and related neurological pathways.
• Chemical Synthesis: Employed in organic synthesis for constructing complex azabicyclic frameworks.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Assays: Applied in in-vitro screening assays to evaluate biological activity and selectivity.

Basic Information

Product Name	(+/-)-2-(3-Pyridinyl)-1-Azabicyclo(2.2.2)Octane Dihydrochloride
CAS No.	1021418-53-0
Molecular Formula	C12H17N3·2HCl
Molecular Weight	276.20 g/mol
Synonyms	2-(Pyridin-3-yl)-1-azabicyclo[2.2.2]octane dihydrochloride; 3-Pyridylquinuclidine dihydrochloride; (±)-2-(3-Pyridyl)quinuclidine dihydrochloride; 1-Azabicyclo[2.2.2]octane, 2-(3-pyridinyl)-, dihydrochloride; 1021418-53-0; 2-(3-Pyridinyl)quinuclidine dihydrochloride; rac-2-(3-Pyridyl)quinuclidine dihydrochloride
EINECS	Contact for details

Quality Control

Our (+/-)-2-(3-Pyridinyl)-1-Azabicyclo(2.2.2)Octane Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.