Description

Ethyl 2-[(2,2,2-Trifluoroethyl)Amino]Acetate (Wxc09054) is a specialized fluorinated amino acid ester building block of significant interest in advanced organic synthesis. Its core value lies in the strategic incorporation of a trifluoroethylamino moiety, which can dramatically alter the physicochemical and metabolic properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries who require high-purity intermediates for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in protease inhibitors, kinase inhibitors, and CNS-active compounds where the trifluoroethyl group enhances lipophilicity and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms contribute to improved biological activity and environmental persistence profiles.
• Peptidomimetics & Bioisosteres: Serves as a valuable building block for creating non-natural amino acids and peptide analogs, enabling the fine-tuning of peptide-based therapeutics.
• Ligand & Catalyst Development: Employed in the synthesis of novel chelating ligands and organocatalysts for asymmetric synthesis and metal complexation.
• Material Science Precursor: Potential use in the synthesis of fluorinated polymers or surface-modifying agents with unique hydrophobic and oleophobic properties.
• Chemical Biology Probe: Useful for incorporating fluorinated tags into biomolecules for studies using techniques such as 19F NMR spectroscopy.

Basic Information

Product Name	Ethyl 2-[(2,2,2-Trifluoroethyl)Amino]Acetate (Wxc09054)
CAS No.	1021002-60-7
Molecular Formula	C6H10F3NO2
Molecular Weight	185.15 g/mol
Synonyms	Ethyl N-(2,2,2-trifluoroethyl)glycinate; Glycine, N-(2,2,2-trifluoroethyl)-, ethyl ester; 2-[(2,2,2-Trifluoroethyl)amino]acetic acid ethyl ester; Ethyl (2,2,2-trifluoroethylamino)acetate; N-(2,2,2-Trifluoroethyl)glycine ethyl ester; WXC-09054; Aminoacetic acid, N-(2,2,2-trifluoroethyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2-[(2,2,2-Trifluoroethyl)Amino]Acetate is produced and analyzed under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.