Description

n-Benzyl-5-Chloro-3-Fluoropyridin-2-Amine is a high-purity, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which enables the introduction of specific functional groups essential for developing novel active compounds. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for use in medicinal chemistry, lead optimization, and the creation of new chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core for bioactivity.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways in academic and industrial research settings.
• Material Science: Potential intermediate for synthesizing specialty chemicals, ligands for catalysis, or monomers for advanced polymers.

Basic Information

Product Name	n-Benzyl-5-Chloro-3-Fluoropyridin-2-Amine
CAS No.	1020253-20-6
Molecular Formula	C₁₂H₁₀ClFN₂
Molecular Weight	236.67 g/mol
Synonyms	2-Amino-5-chloro-3-fluoro-N-benzylpyridine; 5-Chloro-3-fluoro-N-benzylpyridin-2-amine; N-Benzyl-5-chloro-3-fluoropyridin-2-amine; 1020253-20-6; 2-Pyridinamine, 5-chloro-3-fluoro-N-(phenylmethyl)-; 5-Chloro-3-fluoro-2-(benzylamino)pyridine
EINECS	Contact for details

Quality Control

Our n-Benzyl-5-Chloro-3-Fluoropyridin-2-Amine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.