Description

Ethyl 4-Chloro-2-Iodobenzoate is a high-purity, multi-functional organic building block essential for advanced chemical synthesis. Its unique halogenated benzoate structure makes it a critical intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the iodine and chlorine substituents for bioactivity.
• Liquid Crystal Materials: Serves as a building block for halogenated aromatic cores in the production of advanced display materials.
• Organic Ligand Preparation: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings.
• Chemical Research & Development: A versatile reagent for academic and industrial research exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	Ethyl 4-Chloro-2-Iodobenzoate
CAS No.	1020174-06-4
Molecular Formula	C9H8ClIO2
Molecular Weight	310.52 g/mol
Synonyms	Benzoic acid, 4-chloro-2-iodo-, ethyl ester; 4-Chloro-2-iodobenzoic acid ethyl ester; Ethyl 4-chloro-2-iodobenzoate; Ethyl 4-chloro-2-iodobenzenecarboxylate; 2-Iodo-4-chlorobenzoic acid ethyl ester; 1020174-06-4; SCHEMBL2388301; DTXSID70731891
EINECS	Contact for details

Quality Control

Every batch of Ethyl 4-Chloro-2-Iodobenzoate is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.