Description

Ethyl (3-Bromo-5-Fluorobenzoyl)Acetate is a high-purity fluorinated and brominated aromatic building block essential for advanced organic synthesis. This compound matters for its role as a versatile intermediate in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Precursor: Serves as a monomer or intermediate for synthesizing specialty polymers and liquid crystals.
• Chemical Research: Employed in academic and industrial laboratories for method development and exploring new reactions involving halogenated ketones.
• Fluorine Chemistry: A valuable substrate for introducing fluorine atoms into more complex molecules, leveraging the unique properties of fluorine.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille).

Basic Information

Product Name	Ethyl (3-Bromo-5-Fluorobenzoyl)Acetate
CAS No.	1020058-44-9
Molecular Formula	C11H10BrFO3
Molecular Weight	289.10 g/mol
Synonyms	Ethyl 3-bromo-5-fluorobenzoylacetate; Acetic acid, 2-(3-bromo-5-fluorobenzoyl)-, ethyl ester; 3-Bromo-5-fluorobenzoylacetic acid ethyl ester; Ethyl 2-(3-bromo-5-fluorobenzoyl)acetate; (3-Bromo-5-fluorobenzoyl)acetic acid ethyl ester; Ethyl α-(3-bromo-5-fluorobenzoyl)acetate; 1020058-44-9
EINECS	Contact for details

Quality Control

Our Ethyl (3-Bromo-5-Fluorobenzoyl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container must be kept tightly closed in a dry and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.