Description

6-Bromo-3-Chloro-[1,2,4]Triazolo[4,3-A]Pyridine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique fused triazolopyridine scaffold, which serves as a versatile precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or charge-transport molecules.
• Chemical Biology Probes: Utilized in medicinal chemistry to create tool compounds and probes for target identification and validation studies.
• Cross-Coupling Reactions: The bromo and chloro substituents make it an excellent substrate for sequential palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Heterocyclic Library Synthesis: A core building block for generating diverse compound libraries via further functionalization for high-throughput screening.

Basic Information

Item	Detail
Product Name	6-Bromo-3-Chloro-[1,2,4]Triazolo[4,3-A]Pyridine
CAS No.	1020036-34-3
Molecular Formula	C6H2BrClN4
Molecular Weight	245.46 g/mol
Synonyms	6-Bromo-3-chloro-[1,2,4]triazolo[4,3-a]pyridine; 3-Chloro-6-bromo-[1,2,4]triazolo[4,3-a]pyridine; 6-Bromo-3-chloro-1,2,4-triazolo[4,3-a]pyridine; [1,2,4]Triazolo[4,3-a]pyridine, 6-bromo-3-chloro-; 1020036-34-3; 6-Br-3-Cl-[1,2,4]triazolo[4,3-a]pyridine
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Chloro-[1,2,4]Triazolo[4,3-A]Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.