Description

8-Fluoroimidazo[1,2-A]Pyridine-2-Carboxylic Acid is a high-value fluorinated heterocyclic building block essential for modern pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs), enabling the introduction of fluorine to modulate biological activity, metabolic stability, and lipophilicity. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology, CNS disorders, and anti-infective therapies.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides where the fluorine atom enhances efficacy and environmental profile.
• Chemical Biology Probe Development: Serves as a scaffold for creating fluorescent tags or molecular probes to study biological systems.
• Material Science Precursor: Potential monomer or additive for synthesizing specialty polymers and advanced organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and fluoroorganic chemistry.

Basic Information

Product Name	8-Fluoroimidazo[1,2-A]Pyridine-2-Carboxylic Acid
CAS No.	1020034-56-3
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	8-Fluoroimidazo[1,2-a]pyridine-2-carboxylic acid; 2-Imidazo[1,2-a]pyridinecarboxylic acid, 8-fluoro-; 8-Fluoro-2-imidazo[1,2-a]pyridinecarboxylic acid; 8-Fluoroimidazo[1,2-a]pyridine-2-carboxylate; 1020034-56-3; 8-F-Imidazo[1,2-a]pyridine-2-COOH; 8-Fluoro-1H-imidazo[1,2-a]pyridine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 8-Fluoroimidazo[1,2-A]Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.