Description

2-[(Tetrahydro-2-Furanylmethyl)Amino]-Isonicotinic Acid is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. Its value lies in its role as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. This compound is essential for research and development chemists, process chemists, and manufacturers in the global pharmaceutical and biotechnology industries.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural motif for the research and development of new chemical entities with potential therapeutic activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop novel pharmacophores.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale manufacturing of target molecules under current Good Manufacturing Practice (cGMP) guidelines.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	2-[(Tetrahydro-2-Furanylmethyl)Amino]-Isonicotinic Acid
CAS No.	1019452-63-1
Molecular Formula	C12H16N2O3
Molecular Weight	236.27 g/mol
Synonyms	2-[(Tetrahydrofuran-2-ylmethyl)amino]isonicotinic acid; 2-[(Tetrahydro-2-furanylmethyl)amino]-4-pyridinecarboxylic acid; 4-Pyridinecarboxylic acid, 2-[(tetrahydro-2-furanylmethyl)amino]-; 2-[(Oxolan-2-ylmethyl)amino]pyridine-4-carboxylic acid; 1019452-63-1; THF-Methyl-Amino-Isonicotinic Acid; Isonicotinic acid derivative, THF-methylamino substituted
EINECS	Contact for details

Quality Control

Our 2-[(Tetrahydro-2-Furanylmethyl)Amino]-Isonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support development with material produced under quality standards appropriate for preclinical through commercial stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.