Description

2-Chloro-n-(4-Fluorophenyl)Pyridine-4-Carboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated pyridine-carboxamide structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of targeted therapies, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Used in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Agrochemical Intermediate: Potential application in the research and development of new crop protection agents and pesticides.

Basic Information

Product Name	2-Chloro-n-(4-Fluorophenyl)Pyridine-4-Carboxamide
CAS No.	1019383-51-7
Molecular Formula	C12H8ClFN2O
Molecular Weight	250.66 g/mol
Synonyms	2-Chloro-N-(4-fluorophenyl)pyridine-4-carboxamide; 4-Pyridinecarboxamide, 2-chloro-N-(4-fluorophenyl)-; N-(4-Fluorophenyl)-2-chloropyridine-4-carboxamide; 2-Chloro-N-(4-fluorophenyl)isonicotinamide; 1019383-51-7; 2-Chloro-N-(p-fluorophenyl)pyridine-4-carboxamide; 2-Chloro-N-(4'-fluorophenyl)isonicotinamide
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-n-(4-Fluorophenyl)Pyridine-4-Carboxamide adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.