Description

2-Isocyanato-4,5,6,7-tetrahydro-1-benzothiophene is a specialized heterocyclic isocyanate building block, identified by CAS NO 1019374-50-5. This compound is valued for its unique molecular architecture, which combines a saturated bicyclic thiophene core with a highly reactive isocyanate functional group, enabling the synthesis of novel polymers and small molecules. It is primarily sought by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for creating proprietary compounds with tailored properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the synthesis of polyurethanes, polyureas, and other specialty polymers with enhanced thermal or chemical resistance.
• Agrochemical Research: Used in the design and synthesis of new generation herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Employed in the development of advanced coatings, adhesives, and elastomers that require specific performance characteristics.
• Chemical Biology: Useful as a labeling or bioconjugation reagent for probing biological systems and developing diagnostic tools.
• Academic & Industrial R&D: A valuable reagent for methodological studies and exploring new chemical spaces in heterocyclic and medicinal chemistry.

Basic Information

Product Name	2-Isocyanato-4,5,6,7-tetrahydro-1-benzothiophene
CAS No.	1019374-50-5
Molecular Formula	C9H9NOS
Molecular Weight	179.24 g/mol
Synonyms	4,5,6,7-Tetrahydro-1-benzothiophen-2-yl isocyanate; 4,5,6,7-Tetrahydrobenzo[b]thiophen-2-yl isocyanate; 2-Isocyanato-4,5,6,7-tetrahydrobenzo[b]thiophene; Tetrahydrobenzothiophene-2-isocyanate; 2-Isocyanatotetrahydrobenzothiophene
EINECS	Contact for details

Quality Control

Our 2-Isocyanato-4,5,6,7-tetrahydro-1-benzothiophene is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP and ISO 9001 compliant production for critical applications, and specifications can be tailored to meet specific research or development project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as alcohols, amines, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.