Description

6-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-3-Carboxylic Acid is a high-value trifluoromethylated heterocyclic building block essential for modern pharmaceutical and agrochemical research. Its core value lies in the unique physicochemical properties imparted by the imidazopyridine scaffold and the trifluoromethyl group, which are critical for enhancing metabolic stability, lipophilicity, and bioavailability in active molecules. This compound is primarily needed by medicinal chemists and R&D teams in the pharmaceutical industry for the synthesis of novel drug candidates, as well as by researchers in agrochemical development.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves efficacy and environmental stability.
• Material Science: Serves as a precursor for functionalized ligands and organic electronic materials due to its electron-deficient aromatic system.
• Chemical Biology: Employed as a molecular probe or tag in bio-conjugation and proteomics research to study biological interactions.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis and scale-up projects for clients.

Basic Information

Product Name	6-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-3-Carboxylic Acid
CAS No.	1019021-78-3
Molecular Formula	C9H5F3N2O2
Molecular Weight	230.15 g/mol
Synonyms	6-(Trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylic acid; Imidazo[1,2-a]pyridine-3-carboxylic acid, 6-(trifluoromethyl)-; 6-Trifluoromethylimidazo[1,2-a]pyridine-3-carboxylic acid; 6-CF3-Imidazo[1,2-a]pyridine-3-carboxylic acid; 6-(Trifluoromethyl)-3-imidazo[1,2-a]pyridinecarboxylic acid; 1019021-78-3
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under GMP or ISO guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.