Description

4-Amino-2-Chloronicotinic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique molecular structure, which enables the introduction of both amino and chloronicotinic acid functionalities into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates. Its reliable quality and consistent performance make it a critical component in the development of next-generation chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Chemical Research: Serves as a versatile building block in academic and industrial R&D for exploring new heterocyclic chemistry and material science.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal-catalyzed reactions and coordination chemistry.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value, specialty chemicals for various industrial applications.

Basic Information

Product Name	4-Amino-2-Chloronicotinic Acid
CAS No.	1018678-38-0
Molecular Formula	C6H5ClN2O2
Molecular Weight	172.57 g/mol
Synonyms	2-Chloro-4-aminonicotinic Acid; 4-Amino-2-chloropyridine-3-carboxylic Acid; 3-Carboxy-2-chloro-4-aminopyridine; 2-Chloro-4-aminopyridine-3-carboxylic Acid; 4-Amino-2-chloro-3-pyridinecarboxylic Acid; 1018678-38-0; 4-Amino-2-chloronicotinic acid
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Chloronicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.