Description

3-Pyridinecarboxylic Acid, 4-Amino-2-Chloro-, Methyl Ester is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for researchers and manufacturers in fine chemical, pharmaceutical R&D, and agrochemical production who require reliable, high-quality intermediates for constructing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Key synthetic intermediate in the research and development of novel pharmaceutical compounds, particularly for central nervous system (CNS) and anti-infective agents.
• Building block for the synthesis of agrochemicals, including herbicides and insecticides, leveraging its halogenated and amino-substituted pyridine core.
• Precursor in the manufacture of liquid crystal materials and other advanced electronic chemicals.
• Used in academic and industrial organic chemistry research for method development and the creation of complex heterocyclic libraries.
• Intermediate for producing coordination compounds and metal-organic frameworks (MOFs) due to its potential chelating sites.
• Starting material for the synthesis of dyes and pigments with specific light-absorption properties.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 4-Amino-2-Chloro-, Methyl Ester
CAS No.	1018678-37-9
Molecular Formula	C8H9ClN2O2
Molecular Weight	200.62 g/mol
Synonyms	Methyl 4-Amino-2-chloronicotinate; 2-Chloro-4-aminonicotinic Acid Methyl Ester; 4-Amino-2-chloropyridine-3-carboxylic Acid Methyl Ester; 2-Chloro-4-aminopyridine-3-carboxylic Acid Methyl Ester; Methyl 2-Chloro-4-aminonicotinate; 3-Carbomethoxy-2-chloro-4-aminopyridine; 4-Amino-2-chloro-3-pyridinecarboxylic Acid Methyl Ester; 1018678-37-9
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarboxylic Acid, 4-Amino-2-Chloro-, Methyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high standards, such as pharmaceutical R&D under GMP-like conditions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.