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[4-(5-Pyridin-3-Yl-1H-1,2,4-Triazol-3-Yl)Phenyl]Amine CAS NO 1018168-01-8


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CAS No.:1018168-01-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

[4-(5-Pyridin-3-Yl-1H-1,2,4-Triazol-3-Yl)Phenyl]Amine is a high-purity, heterocyclic aromatic amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and functional materials, offering a unique structural motif for creating complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing active pharmaceutical ingredients (APIs), ligands, and specialty polymers.

Application

  • Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or acting as receptor modulators.
  • Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
  • Material Science: Acts as a building block for creating advanced organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
  • Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways and protein interactions.
  • Catalyst Ligand Synthesis: Utilized to develop novel chelating ligands for transition metal catalysts used in asymmetric synthesis and cross-coupling reactions.
  • Academic & Contract Research: A valuable reagent for fundamental organic chemistry research and discovery projects in academic and contract research organizations (CROs).

Basic Information

Product Name [4-(5-Pyridin-3-Yl-1H-1,2,4-Triazol-3-Yl)Phenyl]Amine
CAS No. 1018168-01-8
Molecular Formula C13H11N5
Molecular Weight 237.26 g/mol
Synonyms 4-(5-(Pyridin-3-yl)-1H-1,2,4-triazol-3-yl)aniline; 3-(3-(4-Aminophenyl)-1H-1,2,4-triazol-5-yl)pyridine; 4-(5-Pyridin-3-yl-1H-1,2,4-triazol-3-yl)benzenamine; 1,2,4-Triazole Derivative CAS 1018168-01-8; 4-(5-(3-Pyridyl)-1H-1,2,4-triazol-3-yl)phenylamine; [4-(5-Pyridin-3-yl-1H-[1,2,4]triazol-3-yl)-phenyl]-amine
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Quality Control

Our [4-(5-Pyridin-3-Yl-1H-1,2,4-Triazol-3-Yl)Phenyl]Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance Off-white to light yellow crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 97.0% (Area %)
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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